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1

Out of Africa and into an ice age: on the role of global climate change in the late Pleistocene migration of early modern humans out of Africa

Shannon L. Carto, Andrew J. Weaver, Renée Hetherington, Yin Lam, Edward C. Wiebe

Journal:

Journal of Human Evolution

Year:

2009

Language:

english

File:

PDF, 877 KB

english, 2009

2

The Gospel of Wealth and Other Timely Essays

Wiebe, Robert H., Carnegie, Andrew, Kirkland, Edward C.

Journal:

The Mississippi Valley Historical Review

Year:

1962

Language:

english

File:

PDF, 224 KB

english, 1962

3

Aortoenteric fistula: A rare cause of upper gastrointestinal bleed captured on endoscopy with exceptional clarity

Yang, David Yi, Wiebe, Edward, Peerani, Farhad

Journal:

Digestive and Liver Disease

Year:

2018

Language:

english

File:

PDF, 306 KB

english, 2018

4

Seasonal changes in serum dehydroepiandrosterone, androstenedione, and testosterone levels in the squirrel monkey (Saimiri boliviensis boliviensis)

R. Herbert Wiebe, Lawrence E. Williams, Christian R. Abee, Richard R. Yeoman, Edward J. Diamond

Journal:

American Journal of Primatology

Year:

1988

Language:

english

File:

PDF, 526 KB

english, 1988

5

Synthesis of [5-14C]-1,1,12,12-tetraethoxy-4,9-diazadodecane dinitrate

Vijayalakshmi V. Somayaji, Tse W. Hall, Leonard I. Wiebe, Edward E. Knaus, James P. Demers

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1989

Language:

english

File:

PDF, 269 KB

english, 1989

6

Synthesis and properties of 5-(1,2-dihaloethyl)-2′-deoxyuridines and related analogues

Rakesh Kumar, Edward E. Knaus, Leonard I. Wiebe

Journal:

Journal of Heterocyclic Chemistry

Year:

1991

File:

PDF, 708 KB

1991

7

Climate, African and Beringian subaerial continental shelves, and migration of early peoples

Renée Hetherington, Edward Wiebe, Andrew J. Weaver, Shannon L. Carto, Michael Eby, Roger MacLeod

Journal:

Quaternary International

Year:

2008

Language:

english

File:

PDF, 1.02 MB

english, 2008

8

Pharmacokinetics and Tissue Distribution of (±)-3′-Azido-2′,3′-dideoxy-5′-O-(2-bromomyristoyl)thymidine, a Prodrug of 3′-Azido-2′,3′-dideoxythymidine (AZT) in Mice

Keykavous Parang, Leonard I. Wiebe, Edward E. Knaus

Journal:

Journal of Pharmacy and Pharmacology

Year:

1998

Language:

english

File:

PDF, 732 KB

english, 1998

9

Epilepsy biomarkers

Engel, Jerome, Pitkänen, Asla, Loeb, Jeffrey A., Edward Dudek, F., Bertram, Edward H., Cole, Andrew J., Moshé, Solomon L., Wiebe, Samuel, Jensen, Frances E., Mody, Istvan, Nehlig, Astrid, Vezzani, Ann

Journal:

Year:

2013

Language:

english

File:

PDF, 343 KB

english, 2013

10

Syntheses of [2-2H]-5-ethynyl-1-(β-D-ribofuranosyl)imidazole-4-carboxamide and 5-ethynyl-1-([5-3H]-β-D-ribofuranosyl)imidazole-4-carboxamide (EICAR)

Noriaki Minakawa, Akira Matsuda, Zuping Xia, Leonard I. Wiebe, Edward E. Knaus

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1996

Language:

english

File:

PDF, 654 KB

english, 1996

11

Synthesis and Biological Evaluation of Butanoate, Retinoate, and Bis(2,2,2-trichloroethyl)phosphate Derivatives of 5-Fluoro-2′-deoxyuridine and 2′,5-Difluoro-2′-deoxyuridine as Potential Dual Action Anticancer Prodrugs

Zuping Xia, Leonard I. Wiebe, Gerald G. Miller, Edward E. Knaus

Journal:

Archiv der Pharmazie

Year:

1999

Language:

english

File:

PDF, 126 KB

english, 1999

12

Synthesis and Antifungal Activities of Myristic Acid Analogs

Keykavous Parang, Edward E. Knaus, Leonard I. Wiebe, Soroush Sardari, Mohsen Daneshtalab, Ferenc Csizmadia

Journal:

Archiv der Pharmazie

Year:

1996

Language:

english

File:

PDF, 922 KB

english, 1996

13

Synthesis and Antiviral Activity of 5-Ethyl-5-halo-6-alkoxy-(or Azido)-5,6-dihydro-2′-deoxyuridine Diastereomers as Potential Prodrugs to 5-Ethyl-2′-deoxyuridine

Rakesh Kumar, Leonard I. Wiebe, Edward E. Knaus

Journal:

Archiv der Pharmazie

Year:

1997

Language:

english

File:

PDF, 474 KB

english, 1997

14

Pharmacokinetics and metabolism of the novel synthetic C-nucleoside, 1-(2-deoxy-β-D-ribofuranosyl)-2,4-difluoro- 5-iodobenzene: a potential mimic of 5-iodo-2′-deoxyuridine

Panteha Khalili, Ebrahim Naimi, Edward E. Knaus, Leonard I. Wiebe

Journal:

Biopharmaceutics & Drug Disposition

Year:

2002

Language:

english

File:

PDF, 106 KB

english, 2002

15

Dose-dependent pharmacokinetics of 1-(2-Deoxy-β-D- ribofuranosyl)-2,4-difluoro-5-iodobenzene: A potential mimic of 5-iodo-2′-deoxyuridine

Panteha Khalili, Ebrahim Naimi, Wei Yan Sun, Edward E. Knaus, Leonard I. Wiebe

Journal:

Biopharmaceutics & Drug Disposition

Year:

2003

Language:

english

File:

PDF, 150 KB

english, 2003

16

ChemInform Abstract: Synthesis and Biological Evaluation of Butanoate, Retinoate, and Bis(2,2,2-trichloroethyl)phosphate Derivatives of 5-Fluoro-2′-deoxyuridine and 2′,5-Difluoro-2′-deoxyuridine as Potential Dual Action Anticancer Prodrugs.

Zuping Xia, Leonard I. Wiebe, Gerald G. Miller, Edward E. Knaus

Journal:

Year:

1999

File:

PDF, 26 KB

1999

17

ChemInform Abstract: Syntheses of 4-[1-(2-Deoxy-β-D-ribofuranosyl)] Derivatives of 2-Substituted-5-fluoroaniline: “Cytosine Replacement” Analogues of Deoxycytidine for Evaluation as Anticancer and antihuman Immunodeficiency Virus (anti-HIV) Agents.

Zhi-Xian Wang, Leonard I. Wiebe, Erik De Clercq, Jan Balzarini, Edward E. Knaus

Journal:

Year:

2000

File:

PDF, 34 KB

2000

18

ChemInform Abstract: Synthesis of 1-(2-Deoxy-β-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzene Thymidine Mimics, Some Related α-Anomers, and Their Evaluation as Antiviral and Anticancer Agents.

Zhi-Xian Wang, Weili Duan, Leonard I. Wiebe, Jan Balzarini, Erik De Clercq, Edward E. Knaus

Journal:

Year:

2001

File:

PDF, 37 KB

2001

19

ChemInform Abstract: Synthesis of 1-(2-Deoxy-β-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzenes: “Thymine Replacement” Analogues of Thymidine for Evaluation as Anticancer and Antiviral Agents.

Zhi-Xian Wang, Weili Duan, Leonard I. Wiebe, Jan Balzarini, Erik De Clercq, Edward E. Knaus

Journal:

Year:

2001

File:

PDF, 37 KB

2001

20

ChemInform Abstract: Synthesis of Unnatural 7-Substituted-1-(2-deoxy-β-D-ribofuranosyl)isocarbostyrils: “Thymine Replacement” Analogues of Deoxythymidine for Evaluation as Antiviral and Anticancer Agents.

Ebrahim Naimi, Weili Duan, Leonard I. Wiebe, Edward E. Knaus

Journal:

Year:

2002

File:

PDF, 41 KB

2002

21

ChemInform Abstract: Synthesis of 1-[(2-Hydroxyethoxy)methyl]- and 1-[(1,3-Dihydroxy-2-propoxy)methyl]- Derivatives of 5-Substituted-2,4-difluorobenzene: Unnatural Acyclo Thymidine Mimics for Evaluation as Anticancer and Antiviral Agents.

Zhi-Xian Wang, Weili Duan, Leonard I. Wiebe, Erik De Clercq, Jan Balzarini, Edward E. Knaus

Journal:

Year:

2002

File:

PDF, 33 KB

2002

22

cycloSaligenyl Pronucleotides of 5-Iodo and 5-Trifluoromethyl-1- (2-deoxy-β-D-ribofuranosyl)-2,4-difluorobenzene Mimics of Thymidine: Synthesis and Evaluation of This Pronucleotide Monophosphate Delivery System for Compounds with Potential Anticancer Activity.

Wei Yan Sun, Aihua Zhou, Leonard I. Wiebe, Edward E. Knaus

Journal:

Year:

2004

File:

PDF, 95 KB

2004

23

Synthesis of 1-(2-deoxy-β-D-ribofuranosyl)-2,4- difluoro-5-(2-halo-1-hydroxyethyl)benzenes and related derivatives: “thymine replacement” analogs of deoxythymidine for evaluation as antiviral and anticancer agents

Ebrahim Naimi, Leonard I. Wiebe, Jan Balzarini, Erik De Clercq, Edward E. Knaus

Journal:

Drug Development Research

Year:

2001

Language:

english

File:

PDF, 174 KB

english, 2001

24

Synthesis of 5-(1-azido-2-haloethyl)arabinouridines

Rakesh Kumar, Leonard I. Wiebe, Edward E. Knaus

Journal:

Journal of Heterocyclic Chemistry

Year:

1997

File:

PDF, 152 KB

1997

25

Synthesis of [2-14C]-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-fluoro(chloro)uracil

Hemant K. Misra, Leonard I. Wiebe, Edward E. Knaus

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1987

Language:

english

File:

PDF, 422 KB

english, 1987

26

An improved synthesis of [1-14C]-labelled 2-butynedioic acid, succinic acid and succinyl chloride

Vijayalakshmi V. Somayaji, Tse W. Hall, Leonard I. Wiebe, Edward E. Knaus

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1988

Language:

english

File:

PDF, 236 KB

english, 1988

27

An efficient, high specific activity radioiodination of 5-(1-hydroxy/methoxy-2-iodoethyl)-2′-deoxyuridine by isotope exchange labelling in pivalic acid melt

Takashi Iwashina, Rakesh Kumar, Edward E. Knaus, Leonard I. Wiebe

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1990

Language:

english

File:

PDF, 315 KB

english, 1990

28

Effect of acyclovir on the uptake of 131 I-labelled 1-(2′fluoro-2′-deoxy-βD-D-arabinofuranosyl)-5-lodouracil in herpes infected cells

Dorothy R. Tovell, Harold P. Yacyshyn, Hemant K. Misra, Edward E. Knaus, Leonard I. Wiebe, John Samuel, M. John Gill, D. Lorne J. Tyrrell

Journal:

Journal of Medical Virology

Year:

1987

Language:

english

File:

PDF, 322 KB

english, 1987

29

Synthesis of brain-targeted 1-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-(E)-5-(2-iodovinyl)uracil coupled to a dihydropyridine ⇋ pyridinium salt redox chemical-delivery system

Kevin W. Morin, Leonard I. Wiebe, Edward E. Knaus

Journal:

Carbohydrate Research

Year:

1993

Language:

english

File:

PDF, 615 KB

english, 1993

30

Tumor uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models: VII. [2-14C]-5-ethyl-1-(2′-deoxy-β-D-ribofuranosyl)uracil

Yip W. Lee, Jerzy B. Giziewicz, Edward E. Knaus, Leonard I. Wiebe

Journal:

The International Journal of Applied Radiation and Isotopes

Year:

1984

Language:

english

File:

PDF, 267 KB

english, 1984

31

Tumor uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models: VI. 1-(3′-[36Cl]-chloro-, 1-(3′-[82Br]-bromo- and 1-(3′-[123I]-iodo-3′-deoxy-β-D-arabinofuranosyl)uracil

Yip W. Lee, John R. Mercer, Leonard I. Wiebe, Edward E. Knaus

Journal:

The International Journal of Applied Radiation and Isotopes

Year:

1984

Language:

english

File:

PDF, 370 KB

english, 1984

32

Synthesis of 131I, 125I and 82Br labelled (E)-5-(2-Halovinyl)-2′-deoxyuridines

John Samuel, Edward E. Knaus, Leonard I. Wiebe, D. Lorne Tyrrell

Journal:

The International Journal of Applied Radiation and Isotopes

Year:

1984

Language:

english

File:

PDF, 325 KB

english, 1984

33

Synthesis of [6-36Cl]chlorouracil, [6-82Br]bromouracil and [6-123I]iodouracil

Douglas N. Abrams, Y.W. Lee, Edward E. Knaus, Leonard I. Wiebe

Journal:

The International Journal of Applied Radiation and Isotopes

Year:

1984

Language:

english

File:

PDF, 475 KB

english, 1984

34

The synthesis of radiolabelled 1-(2′-Fluoro-2′-deoxy-β-D-ribofuranosyl)-uracil and 1-(2′-chloro-2′-deoxy-β-D-ribofuranosyl)uracil

Douglas N. Abrams, John R. Mercer, Edward E. Knaus, Leonard I. Wiebe

Journal:

The International Journal of Applied Radiation and Isotopes

Year:

1985

Language:

english

File:

PDF, 680 KB

english, 1985

35

Tumor uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models—VIII. Synthesis and tissue distribution of N-[2-(hydroxyethoxy) methyl]-5-[3H]methyluracil

Yip W. Lee, Takashi Iwashina, Wendy P. Gati, Edward E. Knaus, Leonard I. Wiebe

Journal:

The International Journal of Applied Radiation and Isotopes

Year:

1985

Language:

english

File:

PDF, 349 KB

english, 1985

36

An improved synthesis of 14C-labelled 2,2′-anhydrouridine, 2′-deoxyuridine and 5-ethyl-2′-deoxyuridine

John R. Mercer, Edward E. Knaus, Leonard I. Wiebe

Journal:

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes

Year:

1986

Language:

english

File:

PDF, 734 KB

english, 1986

37

Synthesis of 131I, 125I, 123I and 82Br labelled 5-halo-1-(2-deoxy-2-fluoro-β-d-arabinofuranosyl)uracils

Hemant K. Misra, Edward E. Knaus, Leonard I. Wiebe, D.Lorne Tyrrell

Journal:

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes

Year:

1986

Language:

english

File:

PDF, 325 KB

english, 1986

38

Synthesis and biological properties of (E)-5-(2-[82Br]bromovinyl)-1-(2-deoxy-2-fluoro-β-d-ribofuranosyl)uracil ([82Br]BVFRU)

Takashi Iwashina, Edward E. Knaus, Leonard I. Wiebe, Lihua Xu, D.Lorne Tyrrell, Dorothy R. Tovell

Journal:

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes

Year:

1990

Language:

english

File:

PDF, 370 KB

english, 1990

39

Drug-induced perturbations in the in vivo distribution of oncological radiotracers—II. 5-[125I]iodo-2′-deoxyuridine influenced by nitrobenzylthioinosine-5′-phosphate (NBMPR-P) and acyclothymidine (ACT)

Leonard I. Wiebe, Edward E. Knaus, Wendy P. Gati, Takashi Iwashina, McQueen Lindsay

Journal:

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes

Year:

1990

Language:

english

File:

PDF, 383 KB

english, 1990

40

Radioiodination of 1-(2-deoxy-β-d-ribofuranosyl)-2,4-difluoro-5-iodobenzene (dRFIB), a putative thymidine mimic nucleoside for cell proliferation studies

Anke Stahlschmidt, Hans-Jürgen Machulla, Gerald Reischl, Edward E. Knaus, Leonard I. Wiebe

Journal:

Applied Radiation and Isotopes

Year:

2008

Language:

english

File:

PDF, 338 KB

english, 2008

41

Practice Parameter: Temporal Lobe and Localized Neocortical Resections for Epilepsy : Report of the Quality Standards Subcommittee of the American Academy of Neurology, in Association with the American Epilepsy Society and the American Association of Neurological Surgeons

Jerome Engel Jr., Samuel Wiebe, Jacqueline French, Michael Sperling, Peter Williamson, Dennis Spencer, Robert Gumnit, Catherine Zahn, Edward Westbrook, Bruce Enos

Journal:

Year:

2003

Language:

english

File:

PDF, 103 KB

english, 2003

42

Topical toremifene: a new approach for cutaneous melanoma?

Juhani Maenpaa, Thomas Dooley, Gregory Wurz, John VandeBerg, Edward Robinson, Vernon Emshoff, Pirkko Sipila, Valerie Wiebe, Calvin Day, Michael DeGregorio

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 407 KB

english, 1993

43

The synthesis of [36Cl]-, [82Br]- and [123I]-labelled 1-(3′-chloro-(bromo and iodo)-3′-deoxy-β-D-arabinofuranosyl)uracil

Yip W. Lee, John R. Mercer, Edward E. Knaus, Leonard I. Wiebe

Journal:

The International Journal of Applied Radiation and Isotopes

Year:

1984

Language:

english

File:

PDF, 347 KB

english, 1984

44

Production of 34m Cl from a gaseous hydrogen sulfide target

Douglas N. Abrams, Edward E. Knaus, Leonard I. Wiebe, Frank Helus, Wolfgang Maier-Borst

Journal:

The International Journal of Applied Radiation and Isotopes

Year:

1984

Language:

english

File:

PDF, 344 KB

english, 1984

45

Synthesis of [2-14C]-labelled 2,2′-anhydrouridine and 2'-deoxyuridine derivatives. A convenient route to [2-14C]-labelled 5-ethynyl- and 5-ethyl-2′-deoxyuridine

Jerzy Giziewicz, Lajos J. Gati, Edward E. Knaus, John R. Mercer, Richard J. Flanagan, Leonard I. Wiebe

Journal:

The International Journal of Applied Radiation and Isotopes

Year:

1985

Language:

english

File:

PDF, 526 KB

english, 1985

46

10.1038/29695

Weaver, Andrew J., Eby, Michael, Fanning, Augustus F., Wiebe, Edward C.

Journal:

Year:

1998

Language:

english

File:

PDF, 915 KB

english, 1998

47

A Monte Carlo approach to evolution of the far-infrared luminosity function with BLAST

Gaelen Marsden, Edward L. Chapin, Mark Halpern, Guillaume Patanchon, Douglas Scott, Matthew D. P. Truch, Elisabetta Valiante, Marco P. Viero, Donald V. Wiebe

Journal:

Monthly Notices of the Royal Astronomical Society

Year:

2011

Language:

english

File:

PDF, 5.11 MB

english, 2011

48

Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes

Kyla M. Smith, Amy M. L. Ng, Sylvia Y. M. Yao, Kathy A. Labedz, Edward E. Knaus, Leonard I. Wiebe, Carol E. Cass, Stephen A. Baldwin, Xing-Zhen Chen, Edward Karpinski, James D. Young

Journal:

The Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 277 KB

english, 2004

49

Reaction of 1-(2′,3′-epoxy-β-D-lyxofuranosyl)uracil with hydrogen fluoride. The unexpected formation of 1-(3′-fluoro-3′-deoxy-β-D-ribofuranosyl)uracil

Hemant K. Misra, Wendy P. Gati, Edward E. Knaus, Leonard I. Wiebe

Journal:

Journal of Heterocyclic Chemistry

Year:

1984

File:

PDF, 201 KB

1984

50

Design and synthesis of the 3′-aminocarbonylamino, aminothiocarbonylamino and N-(Hydroxy)guanidinyl derivatives of thymidine as potential anti-HIV agents

Kevin W. Morin, Rakesh Kumar, Edward E. Knaus, Leonard I. Wiebe

Journal:

Journal of Heterocyclic Chemistry

Year:

1991

File:

PDF, 204 KB

1991